Why Storage Matters
Peptides are sensitive biological molecules that can degrade through hydrolysis, oxidation, aggregation, and microbial contamination. Proper storage and handling practices are essential for maintaining peptide integrity and ensuring reliable, reproducible research results.
Lyophilized Storage
Lyophilized (freeze-dried) peptides are the most stable form. Best practices include storage at -20°C or below for long-term stability, keeping vials sealed with desiccant to prevent moisture absorption, protecting from light (especially peptides containing Trp or Tyr), avoiding repeated temperature cycling, and allowing vials to reach room temperature before opening.
Reconstituted Storage
Once reconstituted, peptides have limited stability. General guidelines include storing at 2-8°C (refrigerator), using within 2-4 weeks for most peptides, avoiding freeze-thaw cycles unless validated, using bacteriostatic water for multi-use preparations, and aliquoting into single-use volumes when possible.
Reconstitution Best Practices
Proper reconstitution technique preserves peptide integrity. Use appropriate diluent (bacteriostatic water for most peptides), add diluent slowly along the vial wall, allow natural dissolution without shaking, verify complete dissolution before use, and record concentration and date on the vial.
Common Degradation Pathways
Oxidation: Affects Met, Cys, Trp residues. Prevent with inert gas overlay and antioxidants. Hydrolysis: Breaks peptide bonds. Minimize with proper pH and low temperature. Aggregation: Peptides clump together. Avoid high concentrations and agitation. Microbial contamination: Use aseptic technique and bacteriostatic water.
Full Scale Peptides Quality
All Full Scale Peptides products are shipped in properly sealed, light-protected vials with cold packs when necessary. Our 99%+ purity standard and batch-specific COAs ensure you start with the highest quality material. For laboratory research use only.